Public reference

Colorado Natural Medicine Statistics

A concise, sourced snapshot of Colorado’s regulated natural medicine program and related public survey data. Last updated September 29, 2026.

These figures describe licensing and survey results, not clinical outcomes or the number of people who have received facilitated services.

The program

A new regulated system, in its first licensing year.

Colorado’s Department of Revenue began accepting natural medicine business-license applications on December 31, 2024. Its first public annual report captures approvals through the end of fiscal year 2024-25.

The figures below are deliberately specific about what they count. A licensed healing center, for example, is not the same thing as a licensed facilitator or a completed session.

healing-center licenses

Colorado approved 3 standard and 11 micro healing-center licenses by the end of fiscal year 2024-25.

Source: Colorado Department of Revenue, 2025 annual report, p. 22

cultivation licenses

Three natural medicine cultivation licenses were approved in the program's first licensing period.

Source: Colorado Department of Revenue, 2025 annual report, p. 22

manufacturer licenses

Two product manufacturer licenses were approved by the end of fiscal year 2024-25.

Source: Colorado Department of Revenue, 2025 annual report, p. 22

testing-facility license

One testing-facility license was approved by the end of fiscal year 2024-25.

Source: Colorado Department of Revenue, 2025 annual report, p. 22

129

approved business-role licenses

The state reported 89 approved owner licenses and 40 handler licenses in the same period.

Source: Colorado Department of Revenue, 2025 annual report, p. 22

13.4%

of Colorado adults ages 18–25

used hallucinogens in the past year, according to the 2023-24 annual average. Hallucinogens are a broad category, not a measure of psilocybin alone.

Source: SAMHSA, Behavioral Health Barometer, 2023-24, p. 56

12.1%

of Colorado adults ages 18–25

used hallucinogens in the past year in the preceding 2022-23 annual average.

Source: SAMHSA, state estimates, 2022-23

8.8M

people age 12+ nationwide

reported past-year hallucinogen use in 2023. This national measure includes psilocybin and several other substances.

Source: SAMHSA, 2023 National Survey on Drug Use and Health

How to read the figures

Program data and survey data answer different questions.

Colorado licensing figures show the early shape of the regulated business system. The survey figures show self-reported hallucinogen use in the general population, and should not be read as a count of regulated psilocybin services, a measure of need, or a measure of safety. The national survey’s hallucinogen category includes psilocybin alongside other substances.

For a practical explanation of Colorado’s licensed facilitation process, see how the process works. For current information about this practice’s scope, preparation, and pricing, visit services and pricing.

Methodology and sources

Built from public primary sources.

This page uses the most recent statewide licensing totals located in the Colorado Department of Revenue’s 2025 annual report, plus public federal survey releases. Survey estimates are reported as published, including their age groups and time periods. The page will be reviewed monthly, or sooner when a key source is updated.

Colorado Department of Revenue, 2025 Annual Report, Natural Medicine Division, fiscal year 2024-25, pp. 21-22.
SAMHSA, Behavioral Health Barometer, Division 8, Volume 9, 2023-24 survey estimates, p. 56.
SAMHSA, Colorado state-specific tables, 2022-23 model-based estimates.
SAMHSA, 2023 National Survey on Drug Use and Health, national report.

Cite this page

Colorado Psilocybin Therapy. “Colorado Natural Medicine Statistics.” Updated September 29, 2026. https://coloradopsilocybintherapy.com/colorado-natural-medicine-statistics